An eastbound train derailed several hundred yards east of FM 168.
The derailment led authorities to close FM 168 to traffic at the intersection of Texas 114.
It was closed for one to two hours, according to the Hockley County Sheriffís Office.
A report filed by a sheriffís deputy stated that it appeared the rail bed had collapsed.
Crews with Hulcher Services Inc. were removing damaged rail cars Monday morning.
It was the second train derailment in the county since early June.
Six rail cars filled with corn derailed west of Smyer on June 1 after the rail bed gave way due to erosion caused by heavy rains.
That train of 103 cars was headed to the Diamond Ethanol LLC plant at the time.
This time, a train of 106 cars had unloaded 440,000 bushels of corn at the plant and was headed east when the derailment occurred.
Chuck Fryar, plant manager, said the train came in Saturday, discharged its load in 12 hours and then left after 4 p.m. Sunday.